Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 4
CAF1 p60 Antibody (PA5-92855) in IHC (P)
Immunohistochemistry analysis of CAF1 p60 in paraffin-embedded rat fallopian tube. Samples were incubated with CAF1 p60 Polyclonal antibody (Product # PA5-92855) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-92855
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1 (NP_0054321)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806517
Product Specific Information
Immunogen sequence: SRKNLKRPIA HLPCPGKATL AVRCCPVYFE LRPVVETGVE LMSLPYRLVF AVASEDSVLL YDTQQSFPFG YVSNIHYHTL SDISWSSDGA FLAISSTDGY CSFVTFEKDE LGIPLKEKPV LNMRTPDTAK KTKSQTHRGS SPGPRPVEGT PASRTQDPSS PGTTPPQARQ APAPTVIRDP PSITPAVKSP LPGPSEEKTL QPSSQNTKAH PSRRVTLNTL QAWSKTTPRR INLTPLKTDT PPSSVPTSVI STPSTEEIQS ETPGDAQGSP PELKRPRLDE NKGGTESLDP; Positive Samples: HeLa, 293T, MCF7, U-251MG; Cellular Location: Cytoplasm, Nucleus
Target Information
Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60; CAF1 p60; Chromatin assembly factor 1 subunit B; Chromatin assembly factor I p60 subunit; human chromatin assembly factor-I p60 subunit; M-phase phosphoprotein 7; p60 CAF1; p60-CAF1
Gene Aliases: 2600017H24Rik; C76145; CAF-1; CAF-I p60; CAF-IP60; CAF1; CAF1A; CAF1P60; CHAF1B; MPHOSPH7; MPP7
UniProt ID: (Human) Q13112, (Mouse) Q9D0N7
Entrez Gene ID: (Human) 8208, (Mouse) 110749, (Rat) 288242
positive regulation of defense response to virus by host
DNA replication
DNA repair
DNA replication-dependent nucleosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
protein complex assembly
cell cycle
chromatin assembly
mitophagy in response to mitochondrial depolarization
xenophagy
nucleosome assembly
cellular response to DNA damage stimulus
reproduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support