The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles.
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Protein Aliases: Antigen nuclear dot 52 kDa protein; Calcium-binding and coiled-coil domain-containing protein 2; Nuclear domain 10 protein 52; Nuclear domain 10 protein NDP52; Nuclear dot protein 52
Gene Aliases: CALCOCO2; NDP52
UniProt ID: (Human) Q13137
Entrez Gene ID: (Human) 10241