This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: Jurkat, Raji, NCI-H929, Huh-7, Hep3B, HepG2, Huh-7 (untreated), Huh-7 (3 µM Thapsigargin treatment for 12 hr), Huh-7 (3 µM Thapsigargin treatment for 24 hr), HepG2 (untreated), HepG2 (3 µM Thapsigargin treatment for 12 hr).
Predicted reactivity: Human (99%), Chimpanzee (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles.
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Protein Aliases: Antigen nuclear dot 52 kDa protein; calcium binding and coiled-coil domain 2; Calcium-binding and coiled-coil domain-containing protein 2; NDP52; Nuclear domain 10 protein 52; Nuclear domain 10 protein NDP52; Nuclear dot protein 52
Gene Aliases: CALCOCO2; NDP52
UniProt ID: (Human) Q13137
Entrez Gene ID: (Human) 10241