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Invitrogen
CALCRL Polyclonal Antibody
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FIGURE: 1 / 7
CALCRL Antibody (PA5-33382) in IHC (P)
Immunohistochemistry analysis of CALCRL in Human Pancreas, Positive Staining In Islets of Langerhans, Positive Staining in Macrophages. Samples were incubated with CALCRL polyclonal antibody (Product # PA5-33382). formalin-fixed paraffin-embedded .
Product Details
PA5-33382
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Goat,
Hamster,
Human,
Non-human primate,
Pig,
Rabbit,
Rat,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CALCRL.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CRLR is a receptor for calcitonin gene-related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B-cell/lung/testis, bome marrow, embryo, lung and synovium libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcitonin gene-related peptide type 1 receptor; calcitonin gene-related peptide type 1 receptor-like; calcitonin receptor-like; Calcitonin receptor-like receptor; calcitonin-like peptide type 1 receptor; CGRP receptor; CGRP type 1 receptor; Cgrp1 receptor; CRLR; G protein-coupled receptor
Gene Aliases: CALCRL; CGRPR; CLR; CRLR; RATCRLR; RNCLR
UniProt ID: (Bovine) A6QP74, (Human) Q16602, (Pig) Q8WN93, (Rat) Q63118
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
receptor internalization
angiogenesis
cAMP biosynthetic process
calcium ion transport
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
heart development
protein transport
positive regulation of cAMP biosynthetic process
negative regulation of smooth muscle contraction
positive regulation of smooth muscle cell proliferation
negative regulation of inflammatory response
cellular response to sucrose stimulus
calcitonin gene-related peptide receptor signaling pathway
adrenomedullin receptor signaling pathway
positive regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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