Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to a region derived from internal residues of human calcitonin receptor-like |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2.7 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 40% glycerol |
Contains |
0.05% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2636097 |
The antibody detects endogenous levels of total CALCRL / CRLR protein.
CRLR is a receptor for calcitonin gene-related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B-cell/lung/testis, bome marrow, embryo, lung and synovium libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcitonin gene-related peptide type 1 receptor; Calcitonin receptor-like receptor; CGRP receptor; CGRP type 1 receptor; Cgrp1 receptor
Gene Aliases: CALCRL; CGRPR; CRLR
UniProt ID: (Human) Q16602
Entrez Gene ID: (Human) 10203
Molecular Function:
transmembrane signal receptor
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