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Invitrogen
CALY Polyclonal Antibody
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FIGURE: 1 / 1
CALY Antibody (PA5-87948) in WB
Western blot analysis of CALY in extracts of Mouse testis. Samples were incubated with CALY Polyclonal antibody (Product # PA5-87948) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-87948
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_0565371)
Conjugate
Form
Liquid
Concentration
2.72 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MVKLGCSFSG KPGKDPGDQD GAAMDSVPLI SPLDISQLQP PLPDQVVIKT QTEYQLSSPD QQNFPDLEGQ RLNCSHPEEG RRLPTAR; Positive Samples: Mouse testis; Cellular Location: Cell membrane, Cytoplasmic vesicle membrane, Single-pass membrane protein
Target Information
Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcyon; D1 dopamine receptor-interacting protein; dopamine receptor D1 interacting protein; Neuron-specific vesicular protein calcyon
Gene Aliases: 0710001P07Rik; 1110004A22Rik; Calcyon; Caly; Drd1ip
UniProt ID: (Mouse) Q9D1K9
Entrez Gene ID: (Mouse) 68566
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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