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Proteintech
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Immunogen sequence: MFLVNSFLK GGGGGGGGGG GLGGGLGNVL GGLISGAGGG GGGGGGGGGG GGGGGGGTAM RILGGVISAI SEAAAQYNPE PPPPRTHYSN IEANESEEVR QFRRLFAQLA GDDMEVSATE LMNILNKVVT RHPDLKTDGF GIDTCRSMVA VMDSDTTGKL GFEEFKYLWN NIKRWQAIYK QFDTDRSGTI CSSELPGAFE AAGFHLNEHL YNMIIRRYSD ESGNMDFDNF ISCLVRLDAM FRAFKSLDKD GTGQIQVNIQ EVRTPILGYG CLGGPHPSAL HTSSELQSPS SYFASRPWVR AKGLVLLGFP VLTLHPPLPS GCS (1-323 aa encoded by BC011903)
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; CANP small subunit; CDPS; CSS1; epididymis secretory sperm binding protein; small pol; unnamed protein product
Gene Aliases: CALPAIN4; CANP; CANPS; Capa-4; Capa4; CAPN4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e; PPH6
UniProt ID: (Human) P04632, (Mouse) O88456
Entrez Gene ID: (Human) 826, (Mouse) 12336
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