This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
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Protein Aliases: Ca++-dependent secretion activator; Ca2+ dependent secretion activator; Ca2+-dependent activator protein for secretion; Ca2+-regulated cytoskeletal protein; Calcium-dependent activator protein for secretion 1; Calcium-dependent secretion activator 1; CAPS-1
Gene Aliases: CADPS; CADPS1; CAPS; CAPS1; KIAA1121; UNC-31
UniProt ID: (Human) Q9ULU8
Entrez Gene ID: (Human) 8618
Molecular Function: calcium-binding protein