Proteintech

CAPZA1 Polyclonal Antibody

CAPZA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

CAPZA1 Antibody (11806-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human pancreas cancer using 11806-1-AP (CAPZA1 antibody) at dilution of 1:50 (under 10x lens).

CAPZA1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11806-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CAPZA1 Fusion Protein Ag2267 (1-286 aa encoded by BC000144)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MADFDDRVS DEEKVRIAAK FITHAPPGEF NEVFNDVRLL LNNDNLLREG AAHAFAQYNM DQFTPVKIEG YEDQVLITEH GDLGNSRFLD PRNKISFKFD HLRKEASDPQ PEEADGGLKS WRESCDSALR AYVKDHYSNG FCTVYAKTID GQQTIIACIE SHQFQPKNFW NGRWRSEWKF TITPPTAQVV GVLKIQVHYY EDGNVQLVSH KDVQDSLTVS NEAQTAKEFI KIIENAENEY QTAISENYQT MSDTTFKALR RQLPVTRTKI DWNKILSYKI GKEMQNA (1-286 aa encoded by BC000144)

Target Information

CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Heterodimeric capping protein is required for stereocilia length and width regulation.

The Journal of cell biology

Avenarius MR,Krey JF,Dumont RA,Morgan CP,Benson CB,Vijayakumar S,Cunningham CL,Scheffer DI,Corey DP,Müller U,Jones SM,Barr-Gillespie PG

Mon Nov 06 00:00:00 EST 2017

Heterodimeric capping protein is required for stereocilia length and width regulation.

The Journal of cell biology

Avenarius MR,Krey JF,Dumont RA,Morgan CP,Benson CB,Vijayakumar S,Cunningham CL,Scheffer DI,Corey DP,Müller U,Jones SM,Barr-Gillespie PG

Mon Nov 06 00:00:00 EST 2017

Heterodimeric capping protein is required for stereocilia length and width regulation.

The Journal of cell biology

Avenarius MR,Krey JF,Dumont RA,Morgan CP,Benson CB,Vijayakumar S,Cunningham CL,Scheffer DI,Corey DP,Müller U,Jones SM,Barr-Gillespie PG

Mon Nov 06 00:00:00 EST 2017

Heterodimeric capping protein is required for stereocilia length and width regulation.

The Journal of cell biology

Avenarius MR,Krey JF,Dumont RA,Morgan CP,Benson CB,Vijayakumar S,Cunningham CL,Scheffer DI,Corey DP,Müller U,Jones SM,Barr-Gillespie PG

Mon Nov 06 00:00:00 EST 2017

CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma.

Journal of experimental & clinical cancer research : CR

Huang D,Cao L,Zheng S

Mon Jan 16 00:00:00 EST 2017

CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma.

Journal of experimental & clinical cancer research : CR

Huang D,Cao L,Zheng S

Mon Jan 16 00:00:00 EST 2017

Prognostic value of CAPZA1 overexpression in gastric cancer.

International journal of oncology

Lee YJ,Jeong SH,Hong SC,Cho BI,Ha WS,Park ST,Choi SK,Jung EJ,Ju YT,Jeong CY,Kim JW,Lee CW,Yoo J,Ko GH

Wed May 01 00:00:00 EDT 2013

Prognostic value of CAPZA1 overexpression in gastric cancer.

International journal of oncology

Lee YJ,Jeong SH,Hong SC,Cho BI,Ha WS,Park ST,Choi SK,Jung EJ,Ju YT,Jeong CY,Kim JW,Lee CW,Yoo J,Ko GH

Wed May 01 00:00:00 EDT 2013

Prognostic value of CAPZA1 overexpression in gastric cancer.

International journal of oncology

Lee YJ,Jeong SH,Hong SC,Cho BI,Ha WS,Park ST,Choi SK,Jung EJ,Ju YT,Jeong CY,Kim JW,Lee CW,Yoo J,Ko GH

Wed May 01 00:00:00 EDT 2013

Prognostic value of CAPZA1 overexpression in gastric cancer.

International journal of oncology

Lee YJ,Jeong SH,Hong SC,Cho BI,Ha WS,Park ST,Choi SK,Jung EJ,Ju YT,Jeong CY,Kim JW,Lee CW,Yoo J,Ko GH

Wed May 01 00:00:00 EDT 2013

Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.

Investigative ophthalmology & visual science

Linge A,Kennedy S,O'Flynn D,Beatty S,Moriarty P,Henry M,Clynes M,Larkin A,Meleady P

Mon Jul 09 00:00:00 EDT 2012

Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.

Investigative ophthalmology & visual science

Linge A,Kennedy S,O'Flynn D,Beatty S,Moriarty P,Henry M,Clynes M,Larkin A,Meleady P

Mon Jul 09 00:00:00 EDT 2012

HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Cellular and molecular life sciences : CMLS

Gemoll T,Roblick UJ,Szymczak S,Braunschweig T,Becker S,Igl BW,Bruch HP,Ziegler A,Hellman U,Difilippantonio MJ,Ried T,Jörnvall H,Auer G,Habermann JK

Sat Oct 01 00:00:00 EDT 2011

HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Cellular and molecular life sciences : CMLS

Gemoll T,Roblick UJ,Szymczak S,Braunschweig T,Becker S,Igl BW,Bruch HP,Ziegler A,Hellman U,Difilippantonio MJ,Ried T,Jörnvall H,Auer G,Habermann JK

Sat Oct 01 00:00:00 EDT 2011

HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Cellular and molecular life sciences : CMLS

Gemoll T,Roblick UJ,Szymczak S,Braunschweig T,Becker S,Igl BW,Bruch HP,Ziegler A,Hellman U,Difilippantonio MJ,Ried T,Jörnvall H,Auer G,Habermann JK

Sat Oct 01 00:00:00 EDT 2011

HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.

Cellular and molecular life sciences : CMLS

Gemoll T,Roblick UJ,Szymczak S,Braunschweig T,Becker S,Igl BW,Bruch HP,Ziegler A,Hellman U,Difilippantonio MJ,Ried T,Jörnvall H,Auer G,Habermann JK

Sat Oct 01 00:00:00 EDT 2011

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.

Melanoma research

Sun D,Zhou M,Kowolik CM,Trisal V,Huang Q,Kernstine KH,Lian F,Shen B

Mon Aug 01 00:00:00 EDT 2011

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.

Melanoma research

Sun D,Zhou M,Kowolik CM,Trisal V,Huang Q,Kernstine KH,Lian F,Shen B

Mon Aug 01 00:00:00 EDT 2011

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.

Melanoma research

Sun D,Zhou M,Kowolik CM,Trisal V,Huang Q,Kernstine KH,Lian F,Shen B

Mon Aug 01 00:00:00 EDT 2011

Differential expression patterns of capping protein, protein phosphatase 1, and casein kinase 1 may serve as diagnostic markers for malignant melanoma.

Melanoma research

Sun D,Zhou M,Kowolik CM,Trisal V,Huang Q,Kernstine KH,Lian F,Shen B

Mon Aug 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: Cap Z; capping protein (actin filament) muscle Z-line, alpha 1; capping protein alpha 1; CapZ alpha-1; capZ alpha-1 {ECO:0000250|UniProtKB:P52907}; capza1 {ECO:0000250|UniProtKB:P52907}; F-actin capping protein alpha-1 subunit; F-actin-capping protein subunit alpha-1; F-actin-capping protein subunit alpha-1 {ECO:0000250|UniProtKB:P52907}

View more View less

Gene Aliases: CAPPA1; CAPZ; CAPZA1; CAZ1

View more View less

UniProt ID: (Human) P52907, (Rat) B2GUZ5

View more View less

Entrez Gene ID: (Human) 829, (Rat) 691149, (Mouse) 12340

View more View less

Function(s)

actin binding protein binding cadherin binding involved in cell-cell adhesion actin filament binding non-motor actin binding protein

Process(es)

protein complex assembly movement of cell or subcellular component blood coagulation innate immune response barbed-end actin filament capping cell-cell adhesion actin filament capping

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

CAPZA1 Polyclonal Antibody

CAPZA1 Antibody (11806-1-AP) in IHC (P)

Product Details

11806-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!