Proteintech

CAPZA2 Polyclonal Antibody

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CAPZA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 15948-1-AP (CAPZA2 antibody) at dilution of 1:50 (under 10x lens).

CAPZA2 Antibody in Western Blot (WB) — Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15948-1-AP (CAPZA2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

CAPZA2 Antibody in Immunoprecipitation (IP) — IP result of anti-CAPZA2 (IP:15948-1-AP, 4ug; Detection:15948-1-AP 1:800) with mouse heart tissue lysate 4000ug.

Product Details

15948-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CAPZA2 Fusion Protein Ag8544 (1-286 aa encoded by BC005338) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.23 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MADLEEQLS DEEKVRIAAK FIIHAPPGEF NEVFNDVRLL LNNDNLLREG AAHAFAQYNL DQFTPVKIEG YEDQVLITEH GDLGNGKFLD PKNRICFKFD HLRKEATDPR PCEVENAVES WRTSVETALR AYVKEHYPNG VCTVYGKKID GQQTIIACIE SHQFQAKNFW NGRWRSEWKF TITPSTTQVV GILKIQVHYY EDGNVQLVSH KDIQDSLTVS NEVQTAKEFI KIVEAAENEY QTAISENYQT MSDTTFKALR RQLPVTRTKI DWNKILSYKI GKEMQNA (1-286 aa encoded by BC005338)

Target Information

The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Genes co-amplified with ERBB2 or MET as novel potential cancer-promoting genes in gastric cancer.

Oncotarget

Kwon MJ,Kim RN,Song K,Jeon S,Jeong HM,Kim JS,Han J,Hong S,Oh E,Choi JS,An J,Pollack JR,Choi YL,Park CK,Shin YK

Fri Nov 03 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: capping protein (actin filament) muscle Z-line, alpha 2; capping protein alpha 2; CapZ alpha-2; CAZA2; F-actin capping protein alpha-2 subunit; F-actin-capping protein subunit alpha-2

Gene Aliases: 1110053K06Rik; AW208808; CAPPA2; CAPZ; CAPZA2

UniProt ID: (Human) P47755, (Rat) Q3T1K5, (Mouse) P47754

Entrez Gene ID: (Human) 830, (Rat) 493810, (Mouse) 12343

Molecular Function: non-motor actin binding protein