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Invitrogen
CAR Polyclonal Antibody
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FIGURE: 1 / 4
CAR Antibody (PA5-95066) in WB
Western blot analysis of CAR in Lane 1: human A431 whole cell lysates, Lane 2: human HeLa whole cell lysates, Lane 3: human HepG2 whole cell lysates, Lane 4: human Caco-2 whole cell lysates, Lane 5: human U-937whole cell lysates (negative), Lane 6: human THP-1whole cell lysates (negative). Electrophoresis was performed with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V Resolving gel, Time: 2-3 hours), transferred to a nitrocellulose membrane and blocked using 5% Non-fat Milk/TBS (1.5 hrs at room temperature). Samples were incubated with CAR p... View More
Product Details
PA5-95066
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Coxsackie Adenovirus Receptor (313-328aa YSKTQYNQVPSEDFER).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat liver tissue, rat heart tissue, mouse liver tissue, mouse HEPA1-6 whole cell, human A431 whole cell, human Hela whole cell, human HepG2 whole cell, human Caco-2 whole cell, human U-937whole cell(negative), human THP-1whole cell(negative).|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 46 kD coxsackievirus and adenovirus receptor (CAR) protein; alternatively spliced; CAR; coxsackie virus and adenovirus receptor; Coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; Coxsackievirus B-adenovirus receptor; CVB3-binding protein; CXADR Ig-like cell adhesion molecule; HCVADR; membranous splice variant of CAR1; rCAR; unnamed protein product
Gene Aliases: 2610206D03Rik; AU016810; AW553441; CAR; Car1; CAR4/6; CXADR; HCAR; MCAR; MCVADR
UniProt ID: (Human) P78310, (Mouse) P97792, (Rat) Q9R066
Entrez Gene ID: (Human) 1525, (Mouse) 13052, (Rat) 89843
mitochondrion organization
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
heart development
epithelial structure maintenance
single organismal cell-cell adhesion
neutrophil chemotaxis
actin cytoskeleton reorganization
homotypic cell-cell adhesion
cell-cell junction organization
gamma-delta T cell activation
cardiac muscle fiber development
defense response to virus
negative regulation of cardiac muscle cell proliferation
positive regulation of epithelial cell proliferation involved in wound healing
transepithelial transport
AV node cell to bundle of His cell communication
AV node cell-bundle of His cell adhesion involved in cell communication
regulation of AV node cell action potential
germ cell migration
viral entry into host cell
actin cytoskeleton organization
cardiac muscle cell development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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