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Recommended positive controls: HeLa, HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation; caspase recruitment domain family, member 6; caspase recruitment domain protein 6; Caspase recruitment domain-containing protein 6
Gene Aliases: CARD6; CINCIN1
UniProt ID: (Human) Q9BX69
Entrez Gene ID: (Human) 84674
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