|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from internal of human ALS2CR8.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
The antibody detects endogenous levels of total CARF / ALS2CR8 protein.
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence. Hadano S., Nat. Genet. 29:166-173(2001). Tao X., Neuron 33:383-395(2002). Hillier L.W., Nature 434:724-731(2005)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALS2CR8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; Calcium-responsive transcription factor; CaRF; Testis development protein NYD-SP24
Gene Aliases: ALS2CR8; CARF; NYD-SP24
UniProt ID: (Human) Q8N187
Entrez Gene ID: (Human) 79800
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