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          • Primary Antibodies ›
          • CATSPER3 Antibodies

          Osenses

          CATSPER3 Polyclonal Antibody

          3 References
          View all (3) CATSPER3 antibodies

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          Cite CATSPER3 Polyclonal Antibody

          Additional Information:
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          CATSPER3 Polyclonal Antibody

          Product Details

          OSC00203W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:2,000
          -

          Immunohistochemistry (IHC)

          1:200-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from the c-terminal region of human Cation channel sperm associated protein 3 (CATSPER3) conjugated to an immunogenic carrier protein was used as the antigen
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: CATSPER3.

          Target Information

          CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Ca(v)-like protein; calcium channel repeat containing 1; Cation channel sperm-associated protein 3; CatSper3; One-repeat calcium channel-like protein; putative ion channel CatSper3; unnamed protein product

          View more View less

          Gene Aliases: CACRC; CATSPER3

          View more View less

          UniProt ID: (Human) Q86XQ3

          View more View less

          Entrez Gene ID: (Human) 347732

          View more View less

          Function(s)
          ion channel activity voltage-gated calcium channel activity calcium channel activity
          Process(es)
          ion transport sodium ion transport calcium ion transport spermatogenesis cell differentiation sperm motility ion transmembrane transport sperm capacitation establishment of localization in cell transmembrane transport calcium ion transmembrane transport
          It has to be done as per old AB suggested Products section.

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