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CAZIP Polyclonal Antibody
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FIGURE: 1 / 3
CAZIP Antibody (600-401-AE7) in ICC/IF
Immunofluorescence Microscopy of CAZIP antibody. Tissue: Mouse heart tissue. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: CAZIP antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: CAZIP is cytoplasmic. Staining: CAZIP as red fluorescent signal.
Product Details
600-401-AE7
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-CAZIP antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the C-terminus of human CAZIP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: +TIP of 150 kDa; Cardiac zipper protein; microtubule associated tumor suppressor candidate 2; Microtubule plus-end tracking protein TIP150; Microtubule-associated tumor suppressor candidate 2; Microtubule-associated tumor suppressor candidate 2 homolog; RP11-274A8.2; Tracking protein of 150 kDa; unnamed protein product
Gene Aliases: 5730592G18Rik; A730013O20Rik; AU067634; C130038G02Rik; CAZIP; Gm763; ICIS; KIAA0774; mKIAA0774; MTUS2; TIP150
UniProt ID: (Human) Q5JR59, (Mouse) Q3UHD3
Entrez Gene ID: (Human) 23281, (Mouse) 77521
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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