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Proteintech
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Immunogen sequence: KMFDLNGDGE VDMEEFEQVQ SIIRSQTSMG MRHRDRPTTG NTLKSGLCSA LTTYFFGADL KGKLTIKNFL EFQRKLQHDV LKLEFERHDP VDGRITERQF GGMLLAYSGV QSKKLTAMQR QLKKHFKEGK GLTFQEVENF FTFLKNINDV DTALSFYHMA GASLDKVTMQ QVARTVAKVE LSDHVCDVVF ALFDCDGNGE LSNKEFVSIM KQRLMRGLEK PKDMGFTRLM QAMWKCAQET AWDFALPKQ
MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ara CALC; Atopy-related autoantigen CALC; calcium binding atopy-related autoantigen 1; Calcium uptake protein 1, mitochondrial; Calcium-binding atopy-related autoantigen 1; Calcium-binding atopy-related autoantigen 1 homolog; DKFZp564C246; FLJ12684
Gene Aliases: C730016L05Rik; CALC; CBARA1; EFHA3; MICU1; MPXPS
UniProt ID: (Human) Q9BPX6, (Mouse) Q8VCX5, (Rat) Q6P6Q9
Entrez Gene ID: (Human) 10367, (Mouse) 216001, (Rat) 365567
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