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Proteintech
CBLL1 Polyclonal Antibody
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Product Details
21179-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CBLL1 Fusion Protein Ag15463 (1-227 aa encoded by BC027460)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TDNELQGTN SSGSLGGLDV RRRIPIKLIS KQANKAKPAP RTQRTINRMP AKAPPGDEEG FDYNEEERYD CKGGELFANQ RRFPGHLFWD FQINILGEKD DTPVHFCDKC GLPIKIYGRM IPCKHVFCYD CAILHEKKGD KMCPGCSDPV QRIEQCTRGS LFMCSIVQGC KRTYLSQRDL QAHINHRHMR AGKPVTRASL ENVHPPIAPP PTEIPERFIM PPDKHHMS (1-227 aa encoded by BC027460)
Target Information
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: c-Cbl-like protein 1; Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; Casitas B-lineage lymphoma-transforming sequence-like protein 1; Cbl proto-oncogene like 1, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; E-cadherin binding protein E7; E3 ubiquitin-protein ligase Hakai; RING finger protein 188; RING-type E3 ubiquitin transferase Hakai; unnamed protein product
Gene Aliases: AI467391; c-Cbl-like; CBLL1; HAKAI; RNF188
UniProt ID: (Human) Q75N03, (Mouse) Q9JIY2
Entrez Gene ID: (Human) 79872, (Mouse) 104836
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
identical protein binding
metal ion binding
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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