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Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.
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Protein Aliases: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 20-beta-hydroxysteroid dehydrogenase; Alcohol dehydrogenase [NAD(P)+] CBR1; carbonyl reductase (NADPH) 1; Carbonyl reductase [NADPH] 1; Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1); NADPH-dependent carbonyl reductase 1; PG-9-KR; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase; Short chain dehydrogenase/reductase family 21C member 1; short chain dehydrogenase/reductase family 21C, member 1
Gene Aliases: AW261796; CBR; CBR1; CR; CRN; hCBR1; SDR21C1
UniProt ID: (Human) P16152, (Mouse) P48758
Entrez Gene ID: (Human) 873, (Mouse) 12408
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