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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500 - 1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50 - 1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of CBS (NP_000062.1). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.57 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2913835 |
Positive test controls include: HepG2, 293T, HeLa, MCF7, Mouse liver, Rat liver, Rat kidney. The target is usually found in the following locations: Cytoplasm, Nucleus.
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-thionase; Cystathionine beta-synthase; Cystathionine beta-synthase-like protein; cystathionine-beta-synthase; Hemoprotein H-450; methylcysteine synthase; Serine sulfhydrase
Gene Aliases: AI047524; AI303044; CBS; CBSL; HIP4
UniProt ID: (Human) P35520, (Rat) P32232, (Mouse) Q91WT9
Entrez Gene ID: (Human) 875, (Rat) 24250, (Mouse) 12411
Molecular Function:
lyase
metabolite interconversion enzyme
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