Immunogen sequence: GGSVKDRISL RMIEDAERDG TLKPGDTIIE PTSGNTGIGL ALAAAVRGYR CIIVMPEKMS SEKVDVLRAL GAEIVRTPTN ARFDSPESHV GVAWRLKNEI PNSHILDQYR NASNPLAHYD TTADEILQQC DGKLDMLVAS VGTGGTITGI GAPHR
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-thionase; Cystathionine beta-synthase; Cystathionine beta-synthase-like protein; HIP4; methylcysteine synthase; Serine sulfhydrase
Gene Aliases: CBS; CBSL; HIP4
UniProt ID: (Human) P0DN79
Entrez Gene ID: (Human) 875