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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 161 of Human CBX2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30996 targets CBX2 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-30996 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 161 of Human CBX2.
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CDCA6; cell division cycle associated 6; chromobox homolog 2; chromobox homolog 2 (Pc class homolog; chromobox homolog 2 (Pc class homolog, Drosophila); chromobox protein homolog 2; Drosophila); hromobox homolog 2; M33 polycomb-like protein; modifier 3; modifier 3 protein; Pc class homolog; polycomb; SRXY5
CBX2; CDCA6; M33; MOD2; pc; SRXY5