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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HP1 gamma Antibodies

          Proteintech

          CBX3 Polyclonal Antibody

          33 References
          View all (27) HP1 gamma antibodies

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          Cite CBX3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (7)
          CBX3 Antibody in Immunocytochemistry (ICC/IF)
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          CBX3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          CBX3 Antibody (11650-2-AP) in ICC/IF

          Immunofluorescent analysis of ( 4% PFA ) fixed HepG2 cells using 11650-2-AP (CBX3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          CBX3 Antibody in Immunocytochemistry (ICC/IF)
          CBX3 Antibody in Immunocytochemistry (ICC/IF)
          CBX3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CBX3 Antibody in Western Blot (WB)
          CBX3 Antibody in Western Blot (WB)
          CBX3 Antibody in Western Blot (WB)
          CBX3 Antibody in Immunoprecipitation (IP)
          CBX3 Polyclonal Antibody

          Product Details

          11650-2-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 17 publications 17 publications

          Immunohistochemistry (IHC)

          -
          View 7 publications 7 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 6 publications 6 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication

          ChIP assay (ChIP)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CBX3 Fusion Protein Ag2251 (1-183 aa encoded by BC000954)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.29 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MASNKTTLQ KMGKKQNGKS KKVEEAEPEE FVVEKVLDRR VVNGKVEYFL KWKGFTDADN TWEPEENLDC PELIEAFLNS QKAGKEKDGT KRKSLSDSES DDSKSKKKRD AADKPRGFAR GLDPERIIGA TDSSGELMFL MKWKDSDEAD LVLAKEANMK CPQIVIAFYE ERLTWHSCPE DEAQ (1-183 aa encoded by BC000954)

          Target Information

          At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox protein homolog 3; HECH; heterochromatin protein 1 gamma; Heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; Modifier 2 protein; OTTHUMP00000202463

          View more View less

          Gene Aliases: CBX3; HECH; HP1-GAMMA; HP1g; HP1Hs-gamma; M32

          View more View less

          UniProt ID: (Human) Q13185

          View more View less

          Entrez Gene ID: (Human) 11335, (Mouse) 12417, (Rat) 297093

          View more View less

          Function(s)
          protein binding enzyme binding protein domain specific binding identical protein binding histone methyltransferase binding transcription regulatory region sequence-specific DNA binding molecular_function
          Process(es)
          chromatin remodeling transcription, DNA-templated covalent chromatin modification negative regulation of transcription, DNA-templated rhythmic process cellular response to dexamethasone stimulus regulation of transcription, DNA-templated chromatin modification
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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