Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: ALRISDVHF SVKPSASASS PKLHSSAAVH RLKKDIRRCH RMSRRPLPRP DPQGGSPGLR PPISPFSETV RIINRKVKPR EPKRNRIILN LKVIDKGAGG GGAGQGAGAL ARPKVPSRNR VIGKSKKFSE SVLRTQIRHM KFGAFALYKP PPAPLVAPSP GKAEASAPGP GLLLAAPAAP YDARSSGSSG CPSPTPQSSD PDDTPPKLLP ETVSPSAPSW REPEVLDLSL PPESAATSKR APPEVTAAA (89-336 aa encoded by BC064900)
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromobox homolog 6; Chromobox protein homolog 6
Gene Aliases: CBX6
UniProt ID: (Human) O95503
Entrez Gene ID: (Human) 23466
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