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Product Details
PA5-60621
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human CC2D2A |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2639340 |
Product Specific Information
Immunogen sequence: SVTPNDQCPR AEVSRREDVK KRSVYLKVLF NNKEVSRTVS RPLGADFRVH FGQIFNLQIV NWPESLTLQV YETVGHSSPT LLAEVFLPIP ETTVVTGRAP TEEVEFSSN
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
Target Information
This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil and C2 domain-containing protein 2A
Gene Aliases: CC2D2A; JBTS9; KIAA1345; MKS6
UniProt ID: (Human) Q9P2K1
Entrez Gene ID: (Human) 57545
neural tube closure
smoothened signaling pathway
determination of left/right symmetry
heart development
nonmotile primary cilium assembly
axoneme assembly
cilium assembly
camera-type eye development
motile cilium assembly
cilium morphogenesis
motile primary cilium assembly
embryonic brain development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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