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Product Details
PA5-60621
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CC2D2A. Recombinant protein control fragment (Product #RP-100190).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2639340
Product Specific Information
Immunogen sequence: SVTPNDQCPR AEVSRREDVK KRSVYLKVLF NNKEVSRTVS RPLGADFRVH FGQIFNLQIV NWPESLTLQV YETVGHSSPT LLAEVFLPIP ETTVVTGRAP TEEVEFSSN
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
Target Information
This gene encodes a coiled-coil and calcium binding domain protein that appears to play a critical role in cilia formation. Mutations in this gene cause Meckel syndrome type 6, as well as Joubert syndrome type 9. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil and C2 domain-containing protein 2A
Gene Aliases: CC2D2A; JBTS9; KIAA1345; MKS6
UniProt ID: (Human) Q9P2K1
Entrez Gene ID: (Human) 57545
neural tube closure
smoothened signaling pathway
determination of left/right symmetry
heart development
nonmotile primary cilium assembly
axoneme assembly
cilium assembly
camera-type eye development
motile cilium assembly
cilium morphogenesis
motile primary cilium assembly
embryonic brain development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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