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Bioss
CCDC22 Polyclonal Antibody
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Product Details
BS-8124R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CCDC22, amino acids 525-627.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ccdc22 {ECO:0000250|UniProtKB:O60826}; Coiled-coil domain-containing protein 22; coiled-coil domain-containing protein 22 {ECO:0000250|UniProtKB:O60826}
Gene Aliases: AI481216; CCDC22; CXorf37; DXImx40e; JM1; Ppp1r3f; RGD1560910; RTSC2; Sfc22
UniProt ID: (Human) O60826, (Mouse) Q9JIG7, (Rat) P86182
Entrez Gene ID: (Human) 28952, (Mouse) 54638, (Rat) 317381
cellular copper ion homeostasis
Golgi to plasma membrane transport
cytoplasmic sequestering of NF-kappaB
protein transport
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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