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Invitrogen
CCDC36 Polyclonal Antibody
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Product Details
PA5-84815
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CCDC36. Recombinant protein control fragment (Product #RP-107695).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LCDPREHLVI KQKDGTVEMR GKDKKQQPRK AHRAHRGRLI ASKQKQIPIQ TCKFNSKYQS PQPAISVPQS PFLGQQEPRA QPLHLQCPR
Highest antigen sequence indentity to the following orthologs: Mouse - 29%, Rat - 30%.
Target Information
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 74; coiled-coil domain containing 36; Coiled-coil domain-containing protein 36; CT74; Interactor of HORMAD1 protein 1; unnamed protein product
Gene Aliases: CCDC36; CT74; IHO1; LELA1
UniProt ID: (Human) Q8IYA8
Entrez Gene ID: (Human) 339834
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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