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Product Details
24445-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CCDC53 Fusion Protein Ag19831 (1-194 aa encoded by BC010889)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDEDGLPLM GSGIDLTKVP AIQQKRTVAF LNQFVVHTVQ FLNRFSTVCE EKLADLSLRI QQIETTLNIL DAKLSSIPGL DDVTVEVSPL NVTSVTNGAH PEATSEQPQQ SSTQDSGLQE SEVSAENILT VAKDPRYARY LKMVQVGVPV MAIRNKMISE GLDPDLLERP DAPVPDGESE KTVEESSDSE SSFSD (1-194 aa encoded by BC010889)
Target Information
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 53; WASH complex subunit 3
Gene Aliases: AD-016; CCDC53; CGI-116; WASHC3; x0009
UniProt ID: (Human) Q9Y3C0
Entrez Gene ID: (Human) 51019
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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