This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.
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Protein Aliases: Coiled-coil domain-containing protein 6; Papillary thyroid carcinoma-encoded protein; Protein H4
Gene Aliases: CCDC6; D10S170; H4; PTC; TPC; TST1
UniProt ID: (Human) Q16204
Entrez Gene ID: (Human) 8030