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Proteintech
CCDC91 Polyclonal Antibody
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Product Details
31097-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CCDC91 fusion protein Ag34863
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MPMWNKVSGV HLSPSSPEIV LDRDHSSSIG CLSSDAIISS PENTHAANSI VSQTIPKAQI QQSTHTHLDI SLFPLGLTDE KSNGTIALVD DSEDPGANVS NIQLQQKISS LEIKLKVSEE EKQRIKQDVE SLMEKHNVLE KGFLKEKEQE AISFQDRYKE LQEKHKQELE DMRKAGHEAL SIIVDEYKAL LQSSVKQQVE
Target Information
CCDC91 (Coiled-Coil Domain-Containing 91) is a gene located on chromosome 12q24.31 that encodes a protein involved in vesicle-mediated transport and Golgi function. The CCDC91 protein contains coiled-coil domains, which facilitate protein-protein interactions necessary for its role in the secretory pathway. Specifically, CCDC91 is a component of the Golgi-associated retrograde protein (GARP) complex, which is essential for the recycling of transport vesicles from endosomes to the trans-Golgi network (TGN). Research has revealed that CCDC91 is crucial for maintaining Golgi structure and function and is involved in the sorting and trafficking of proteins and lipids within the cell. The protein's interactions with other components of the vesicular transport machinery enable the efficient movement of cargo between organelles, which is critical for various cellular processes, including secretion, endocytosis, and lysosomal degradation. Mutations or dysregulation of CCDC91 can disrupt these processes, potentially leading to diseases associated with vesicle trafficking defects, such as certain neurodegenerative disorders and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 91; FLJ11088; GGA binding partner; GGA-binding partner; p56 accessory protein; unnamed protein product
Gene Aliases: 1700086G08Rik; 1810060J02Rik; AU045683; AW555238; CCDC91; GGABP; HSD8; p56
UniProt ID: (Human) Q7Z6B0, (Mouse) Q9D8L5, (Rat) Q6AY97
Entrez Gene ID: (Human) 55297, (Mouse) 67015, (Rat) 312863
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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