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Invitrogen
CCK Polyclonal Antibody
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FIGURE: 1 / 3
CCK Antibody (PA5-103116) in ICC/IF
Immunofluorescent analysis of CCK in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CCK polyclonal antibody (Product # PA5-103116) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-103116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Horse,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CCK(Accession P06307), corresponding to amino acid residues Q68-S115.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Cholecystokinin/CCK.
Target Information
Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). Antibodies that react specifically with CCK are useful for the study of the mode of action, differential tissue expression and intracellular and subcellular localization of CCK in the CNS and periphery as well as in neuroendocrine cells of the digestive system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CCK; Cholecystokinin; cholecystokinin octapeptide; cholecystokinin triacontatriapeptide; prepro-cholecystokinin; unnamed protein product
Gene Aliases: CCK
UniProt ID: (Human) P06307, (Rat) P01355, (Mouse) P09240
Entrez Gene ID: (Human) 885, (Rat) 25298, (Mouse) 12424
behavioral fear response
neuron migration
release of cytochrome c from mitochondria
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
positive regulation of cell proliferation
negative regulation of appetite
positive regulation of protein oligomerization
eating behavior
positive regulation of apoptotic process
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of mitochondrial depolarization
regulation of sensory perception of pain
signal transduction
digestion
cholecystokinin signaling pathway
positive regulation of glutamate secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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