Invitrogen

CCK Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

1 Published Figure

3 References

View all (7) CCK antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

CCK Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 7

CCK Antibody (PA5-84814) in IHC (P)

Immunohistochemical analysis of CCK in human small intestine using CCK Polyclonal Antibody (Product # PA5-84814) shows strong cytoplasmic positivity in endocrine glandular cells.

Product Image Gallery

CCK Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CCK demonstrates antibody specificity. Immunohistochemical analysis of CCK using anti-CCK Polyclonal Antibody (Product #PA5-84814), shows significant staining of CCK in duodenum and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of CCK within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-84814

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

Functional Assay (Functional)

View 1 publication 1 publication

In vitro Assay (IV)

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CCK. Recombinant protein control fragment (Product #RP-106081).

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Anitgen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791963

Product Specific Information

Immunogen sequence: LQRAEEAPRR QLRVSQRTDG ESRAHLGALL ARYIQQARKA PSGRMSIVKN LQNLDPSHRI SDRDYMG

Target Information

Cholecystokinin (CCK) is a neuropeptide hormone and neurotransmitter widely distributed throughout the gastrointestinal (GI) tract and the central nervous system (CNS). Antibodies that react specifically with CCK are useful for the study of the mode of action, differential tissue expression and intracellular and subcellular localization of CCK in the CNS and periphery as well as in neuroendocrine cells of the digestive system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

AMOTL2‑knockdown promotes the proliferation, migration and invasion of glioma by regulating β‑catenin nuclear localization.

Oncology reports

Chen X,Lu Y,Guo G,Zhang Y,Sun Y,Guo L,Li R,Nan Y,Yang X,Dong J,Jin X,Huang Q

Published figure using CCK polyclonal antibody (Product # PA5-84814) in In vitro Assay

Thu Jul 01 00:00:00 UTC 2021

AMOTL2‑knockdown promotes the proliferation, migration and invasion of glioma by regulating β‑catenin nuclear localization.

Oncology reports

Chen X,Lu Y,Guo G,Zhang Y,Sun Y,Guo L,Li R,Nan Y,Yang X,Dong J,Jin X,Huang Q

Published figure using CCK polyclonal antibody (Product # PA5-84814) in In vitro Assay

Thu Jul 01 00:00:00 UTC 2021

AMOTL2‑knockdown promotes the proliferation, migration and invasion of glioma by regulating β‑catenin nuclear localization.

Oncology reports

Chen X,Lu Y,Guo G,Zhang Y,Sun Y,Guo L,Li R,Nan Y,Yang X,Dong J,Jin X,Huang Q

Published figure using CCK polyclonal antibody (Product # PA5-84814) in In vitro Assay

Thu Jul 01 00:00:00 UTC 2021

Mechanism underlying long non‑coding RNA ILF3‑AS1‑mediated inhibition of cervical cancer cell proliferation, invasion and migration, and promotion of apoptosis.

Molecular medicine reports

Zhu L,Chen R,Jiang C,Xie Q,Zhao W,Gao X,Huang H

PA5-84814 was used in Functional assay to analyse the effects of long non‚coding RNA ILF3 divergent transcript and it's potential target, miR‚454‚3p, on cervical cancer outcomes.

Sun Aug 01 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: CCK; Cholecystokinin; cholecystokinin octapeptide; cholecystokinin triacontatriapeptide; prepro-cholecystokinin

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Gene Aliases: CCK

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UniProt ID: (Human) P06307

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Entrez Gene ID: (Human) 885

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Function(s)

hormone activity neuropeptide hormone activity

Process(es)

behavioral fear response neuron migration release of cytochrome c from mitochondria activation of cysteine-type endopeptidase activity involved in apoptotic process signal transduction protein kinase C-activating G-protein coupled receptor signaling pathway axonogenesis positive regulation of cell proliferation positive regulation of glutamate secretion negative regulation of appetite positive regulation of protein oligomerization eating behavior positive regulation of peptidyl-tyrosine phosphorylation positive regulation of mitochondrial depolarization regulation of sensory perception of pain

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CCK Polyclonal Antibody

CCK Antibody (PA5-84814) in IHC (P)

Product Details

PA5-84814

Immunohistochemistry (Paraffin) (IHC (P))

Functional Assay (Functional)

In vitro Assay (IV)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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