PA1-24544 detects Cholecystokinin A Receptor in Human samples.
PA1-24544 has been successfully used in Immunohistochemistry (paraffin) procedures.
PA1-24544 immunogen corresponds to Synthetic peptide - KLH conjugated. Sequence identity/similarity to Mouse: 35/55%. Rat: 65/70%.
Cholecystokinin A receptor, a Cholecystokinin Receptor, binds sulfated CCK, particularly CCK8. The CCKA receptor mediates gallbladder contraction, gastric emptying, relaxation of the sphincter of Oddi, and insulin secretion. It is also inolved in pancreatic growth, enzyme secretion, and tumorigenesis. Cholecystokinin A receptor has been reported in brain, colon, gall bladder, gastrointestinal tract, kidney, pancreas, small intestine, spinal cord, and stomach. ESTs have been isolated from mouse kidney and heart libraries.
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Protein Aliases: CCK-A receptor; CCK-AR; CCK1-R; Cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor
Gene Aliases: CCK-A; CCK1-R; CCK1R; CCKAR; CCKRA
UniProt ID: (Human) P32238
Entrez Gene ID: (Human) 886