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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 23-52 amino acids from the central region of human CCL21|
|Purification||Protein A, Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
6Ckine; beta chemokine exodus-2; Beta-chemokine exodus-2; C-C motif chemokine 21; C-C motif chemokine 21a; chemokine (C-C motif) ligand 21; CKb9; Efficient Chemoattractant for Lymphocytes; exodus-2; member 21; predicted gene 1987; SCYA21; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; sma; small inducible cytokine subfamily A (Cys-Cys); small inducible cytokine subfamily A (Cys-Cys), member 21; Small-inducible cytokine A21; Small-inducible cytokine A21a; TCA4; Thymus-derived chemotactic agent 4
100038965; 6Ckine; CCL21; Ccl21a; CKb9; ECL; SCYA21; Scya21a; SLC; TCA4; UNQ784/PRO1600