This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: KELWVQQLMQ HLDKTPSPQK PAQGCRKDRG ASKTGKKGKG SKGCKRTERS QT
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
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Protein Aliases: 6 Ckine; 6Ckine; beta chemokine exodus-2; Beta-chemokine exodus-2; C-C motif chemokine 21; chemokine (C-C motif) ligand 21; Efficient Chemoattractant for Lymphocytes; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; sma; small inducible cytokine subfamily A (Cys-Cys), member 21; Small-inducible cytokine A21
Gene Aliases: 6Ckine; CCL21; CKb9; ECL; SCYA21; SLC; TCA4; UNQ784/PRO1600
UniProt ID: (Human) O00585
Entrez Gene ID: (Human) 6366