This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated. View Details
In sandwich ELISAs, less than 0.02% cross-reactivity with recombinant human RANTES, recombinant mouse RANTES, and recombinant cotton rat RANTES is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-C motif chemokine 5; MGC17164; OTTHUMP00000197106; SIS ¿¿; SIS¿¿; small inducible cytokine A5; Small-inducible cytokine A5; T-cell-specific protein RANTES
Gene Aliases: CCL5; RANTES; SCYA5
UniProt ID: (Cat) Q8SQ40
Entrez Gene ID: (Cat) 493689