Keep as concentrated solution.
Positive Control: RANTES transfected 293T cell.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: and presumably secreted antibody; beta-chemokine RANTES; beta-chemokine RANTES antibody; C-C motif chemokine 5; C-C motif chemokine 5 antibody; CCL5 antibody; chemokine (C-C motif) ligand 5; chemokine (C-C motif) ligand 5 antibody; D17S136E antibody; EoCP; eoCP antibody; Eosinophil chemotactic cytokine; eosinophil chemotactic cytokine antibody; member 5 antibody; MGC17164 antibody; normally T-expressed; RANTES antibody; RANTES(3-68); RANTES(4-68); regulated upon activation; regulated upon activation, normally T-expressed, and presumably secreted; SCYA5 antibody; SIS-delta; SIS-delta antibody; SISd antibody; small inducible cytokine A5 (RANTES) antibody; small inducible cytokine subfamily A (Cys-Cys); small inducible cytokine subfamily A (Cys-Cys), member 5; Small-inducible cytokine A5; small-inducible cytokine A5 antibody; T cell-specific protein P228; t cell-specific protein P228 antibody; T-cell specific protein p288; T-cell specific protein p288 antibody; T-cell-specific protein RANTES; T-cell-specific protein RANTES antibody; TCP228; TCP228 antibody
Gene Aliases: CCL5; D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
UniProt ID: (Human) P13501
Entrez Gene ID: (Human) 6352