OriGene

CCNA2 Polyclonal Antibody

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CCNA2 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCNA2(RC211148, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CCNA2 r. Positive lysates LY400494 (100 µg) and LC400494 (20 µg) can be purchased separately from OriGene.

Product Details

TA890057

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein of human CCNA2

Conjugate

Unconjugated

Form

liquid

Concentration

3.92 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Target Information

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer.

Oncotarget

Cirillo F,Pellegrino M,Malivindi R,Rago V,Avino S,Muto L,Dolce V,Vivacqua A,Rigiracciolo DC,De Marco P,Sebastiani A,Abonante S,Nakajima M,Lappano R,Maggiolini M