OriGene

CCNA2 Polyclonal Antibody

Product Image Gallery

CCNA2 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCNA2(RC211148, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CCNA2 r. Positive lysates LY400494 (100 µg) and LC400494 (20 µg) can be purchased separately from OriGene.

Product Details

TA890057

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:2,000	-
Miscellaneous PubMed (Misc)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse
Published species	Not Applicable
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein of human CCNA2
Conjugate	Unconjugated
Form	liquid
Concentration	3.92 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Target Information

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer.

Oncotarget

Cirillo F,Pellegrino M,Malivindi R,Rago V,Avino S,Muto L,Dolce V,Vivacqua A,Rigiracciolo DC,De Marco P,Sebastiani A,Abonante S,Nakajima M,Lappano R,Maggiolini M