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          • Primary Antibodies ›
          • Cyclin C Antibodies

          Abnova

          CCNC Polyclonal Antibody, MaxPab™

          View all (11) Cyclin C antibodies

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          Cite CCNC Polyclonal Antibody, MaxPab™

          Additional Information:
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          • Antibody Testing Data (1)
          CCNC Antibody in Western Blot (WB)
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          CCNC Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CCNC Antibody (H00000892-B02P) in WB

          Western Blot analysis of CCNC expression in transfected 293T cell line by CCNC MaxPab polyclonal antibody. Lane 1: CCNC transfected lysate(31.00 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CCNC Antibody in Western Blot (WB)
          CCNC Polyclonal Antibody, MaxPab™

          Product Details

          H00000892-B02P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CCNC (NP_005181.2, 1 a.a. approximately 283 a.a) full-length human protein.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1 mg/mL

          Amount

          50 µg

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Product may be used with Western Blot (Transfected lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: MAGNFWQSSH YLQWILDKQD LLKERQKDLK FLSEEEYWKL QIFFTNVIQA LGEHLKLRQQ VIATATVYFK RFYARYSLKS IDPVLMAPTC VFLASKVEEF GVVSNTRLIA AATSVLKTRF SYAFPKEFPY RMNHILECEF YLLELMDCCL IVYHPYRPLL QYVQDMGQED MLLPLAWRIV NDTYRTDLCL LYPPFMIALA CLHVACVVQQ KDARQWFAEL SVDMEKILEI IRVILKLYEQ WKNFDERKEM ATILSKMPKP KPPPNSEGEQ GPNGSQNSSY SQS

          Target Information

          Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cyclin-C; hSRB11; SRB11 homolog; unnamed protein product

          View more View less

          Gene Aliases: CCNC; CycC; hSRB11; SRB11

          View more View less

          UniProt ID: (Human) P24863

          View more View less

          Entrez Gene ID: (Human) 892

          View more View less

          Function(s)
          protein binding cyclin-dependent protein serine/threonine kinase regulator activity identical protein binding
          Process(es)
          regulation of transcription from RNA polymerase II promoter G0 to G1 transition negative regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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