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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence C-TKASHVTPQPED, from the internal region near the C-terminus of CCNDBP1 (aa322-333)|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with dog, pig and cow based on sequence homology.
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cyclin D-type binding-protein 1; cyclin-D1-binding protein 1; D-type cyclin-interacting protein 1; DIP1; GCIP; grap2 and cyclin D interacting protein; grap2 and cyclin-D-interacting protein; HHM; human homolog of Maid
CCNDBP1; DIP1; GCIP; HHM