Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Endoglin (Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia.
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Protein Aliases: CD105; Cell surface MJ7/18 antigen; Edg; Endoglin; Eng; transmembrane glycoprotein
Gene Aliases: AI528660; AI662476; CD105; Edg; Endo; Eng; S-endoglin
UniProt ID: (Mouse) Q63961