Immunogen sequence: KLYWSKVKAE PSEKVSLRIS VTQPDSIVGI VAVDKSVNLM NASNDITMEN
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Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Pig: 92%; Rat: 100%
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
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Protein Aliases: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; Gov platelet alloantigens; p180; Platelet-specific Gov antigen; r150; RP11-525G3.1
Gene Aliases: CD109; CPAMD7; p180; r150
UniProt ID: (Human) Q6YHK3
Entrez Gene ID: (Human) 135228