Immunogen sequence: GPVEILTTVT ESVTGISRNV STNVFFKQHD YIIEFFDYTT VLKPSLNFTA TVKVTRADGN QLTLEERRNN VVITVTQRNY TEYWSGSNSG NQKMEAVQKI NYTVPQSGTF KIEFPILEDS SELQLKAYFL GSKSSMA
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
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Protein Aliases: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; CPAMD7; DKFZp762L1111; FLJ38569; Gov platelet alloantigens; p180; Platelet-specific Gov antigen; r150
Gene Aliases: CD109; CPAMD7; p180; r150
UniProt ID: (Human) Q6YHK3
Entrez Gene ID: (Human) 135228