This Antibody was verified by IP Mass Spectrometry to ensure that the antibody binds to the antigen stated. View Details
PA5-16918 targets CD138 in IHC applications and shows reactivity with Human samples.
The PA5-16918 immunogen is recombinant protein encoding aa 18-218 human CD138.
CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence is a useful marker for viable myeloma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; SDC; SDC1; SYND1; syndecan proteoglycan 1; Syndecan-1; synstatin
Gene Aliases: AA408134; AA409076; CD138; SDC; SDC1; Sstn; syn-1; Synd; Synd-1; SYND1; syndecan
Molecular Function: cell adhesion molecule cytoskeletal protein defense/immunity protein extracellular matrix glycoprotein extracellular matrix protein membrane-bound signaling molecule signaling molecule