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CD147 Polyclonal Antibody
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Product Details
BS-0684R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CD147/TCSF, amino acids 301-385.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5A11/Basigin; 5F7; adhesion molecule; amino acid feature: intracellular domain, aa 707 .. 829; amino acid feature: transmembrane domain, aa 638 .. 706; amino acid feature: extracellular domain, aa 86 .. 637; Basic immunoglobulin superfamily; Basigin; Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); CD147; CD147 antigen; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HAb18G; Hepatoma-associated antigen; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK blood group antigen; OX-47 antigen; retinal glycoprotein; TCSF; Tumor cell-derived collagenase stimulatory factor; unnamed protein product
Gene Aliases: 5A11; 5F7; AI115436; AI325119; basignin; BSG; CD147; CE9; EMMPRIN; EMPRIN; HAb18G; HT-7; HT7; OK; Ox47R; TCSF; UNQ6505/PRO21383
UniProt ID: (Human) P35613, (Rabbit) Q28740, (Mouse) P18572, (Rat) P26453
Entrez Gene ID: (Human) 682, (Rabbit) 100339001, (Rabbit) 100009229, (Mouse) 12215, (Rat) 25246
angiogenesis
neural retina development
homophilic cell adhesion via plasma membrane adhesion molecules
cell surface receptor signaling pathway
axon guidance
embryo implantation
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
neutrophil chemotaxis
positive regulation of interleukin-6 production
odontogenesis of dentin-containing tooth
response to peptide hormone
photoreceptor cell maintenance
positive regulation of viral entry into host cell
response to mercury ion
decidualization
viral entry into host cell
response to cAMP
endothelial tube morphogenesis
dendrite self-avoidance
protein localization to plasma membrane
positive regulation of matrix metallopeptidase secretion
neuron projection extension
protein targeting to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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