Cloud
| Details | |
|---|---|
| Tested species reactivity | Human |
| Published species reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G8 |
| Immunogen | Human CD16 |
| Conjugate | APC |
| Form | Liquid |
| Purification | purified |
| Storage buffer | PBS with BSA, sucrose |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4° C, store in dark |
| Tested Applications | Dilution * |
|---|---|
| Flow Cytometry (Flow) | Assay-Dependent |
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
| Published Applications | |
|---|---|
| Flow Cytometry (Flow) | See 2 publications below |
Allophycocyanin (APC) is a stable and highly soluble phycobiliprotein that provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing exceptional quantum yields and molar extinction coefficients.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Analyte Specific Reagent
| Species | Dilution | Title | Authors | Journal (Vol:Pg) | Year |
|---|---|---|---|---|---|
| Human | Not Cited |
Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.
MHCD1605 was used in flow cytometry to study the immediate innate immune response after an ischemic insult. |
Algra SO,Groeneveld KM,Schadenberg AW,Haas F,Evens FC,Meerding J,Koenderman L,Jansen NJ,Prakken BJ | Journal of neuroinflammation (10:null) | 2013 |
| Human | Not Cited |
Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans.
MHCD1605 was used in flow cytometry to study heme oxygenase- in HIV-infected people. |
Seu L,Burt TD,Witte JS,Martin JN,Deeks SG,McCune JM | Genes and immunity (13:258) | 2012 |
CD16a antigen, Fc fragment of IgG, low affinity III, receptor for (CD16), Fc gamma receptor III-A, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), FcgammaRIIIA, fc-gamma RIII, igG Fc receptor III-2, immunoglobulin G Fc receptor III, low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA, Fc fragment of IgG, low affinity IIIb, receptor for (CD16), Fc-gamma receptor IIIb (CD 16), fc-gamma RIII-beta, fc-gamma RIIIb, igG Fc receptor III-1, low affinity immunoglobulin gamma Fc region receptor III-B, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
RP11-5K23.1, FCRIIIb, RP11-25K21.3, FCRIIIA, FCG3, IGFR3, FCGR3, CD16b, CD16A, FCGRIII, CD16, FCRIII, FCR-10
Immunity and defense
B-cell- and antibody-mediated immunity
Macrophage-mediated immunity
Receptor
Defense/immunity protein
Immunoglobulin receptor family member
© 2016 Thermo Fisher Scientific Inc. All Rights Reserved.
