The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
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Protein Aliases: CD169; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; Sialoadhesin; Siglec-1
Gene Aliases: CD169; dJ1009E24.1; SIGLEC-1; SIGLEC1; SN
UniProt ID: (Human) Q9BZZ2
Entrez Gene ID: (Human) 6614