The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.
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Protein Aliases: CD179 antigen-like family member A; CD179a; Immunoglobulin iota chain; Protein VPreB1; V(pre)B protein; VpreB protein
Gene Aliases: CD179a; IGI; IGVPB; VPREB; VPREB1
UniProt ID: (Human) P12018
Entrez Gene ID: (Human) 7441