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Invitrogen
CD179b Polyclonal Antibody
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FIGURE: 1 / 6
CD179b Antibody (PA5-95623) in IHC (P)
Immunohistochemistry analysis of CD179b in paraffin-embedded human B lymphocytic tumor tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with CD179b polyclonal antibody (Product # PA5-95623) at a 1 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavidin-Biotin-... View More
Product Details
PA5-95623
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human IGLL1 recombinant protein (L38-S213).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue. IHC: human B lymphocytic tumor tissue, human tonsil tissue, human tonsil tissue, mouse spleen tissue, rat spleen tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The preB cell receptor, CD179b, is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation and differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda-5; IGLJ IGLL; immunoglobulin lambda chain 5; Immunoglobulin lambda-like polypeptide 1; immunoglobulin lambda-like polypeptide 5; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; Immunoglobulin-related protein 14.1; lambda 5; lambda5; Pre-B lymphocyte-specific protein-2
Gene Aliases: 14.1; AGM2; BB139905; CD179b; Igl-5; IGL1; IGL5; IGLJ14.1; IGLL; IGLL1; IGO; IGVPB; Lambda5; VPREB2
UniProt ID: (Human) P15814, (Mouse) P20764
Entrez Gene ID: (Human) 3543, (Mouse) 16136, (Rat) 100360919
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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