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CD2/CD7 Antibody Cocktail, FITC, PE
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Product Details
0027S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
Class
Cocktail
Type
Antibody
Immunogen
CD2 was derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with t lymphocytes activated by mixed lymphocyte culture. CD7 was derived from the hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells of BALB/c mice immunized with T-acute lymphoblastic leukemia (T-ALL) cells.
Conjugate
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Flow Cytometry PBMC: Add 10 µL of MAB/10^6 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 2 to 8C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze.
Flow Cytometry Whole Blood: Add10 µL of MAB/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature 20C. Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer instructions for Lysed Whole Blood and Immunofluorescence analysis with a flow cytometer or microscope.
Target Information
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2CD2 antigen; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 surface antigen; CD7; CD7 antigen (p41); Erythrocyte receptor; GP40; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; p41 protein; Rosette receptor; surface antigen CD2 precursor; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen CD2 precursor; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; TP41; unnamed protein product
Gene Aliases: CD2; CD7; GP40; LEU-9; LFA-2; SRBC; T11; Tp40; TP41
UniProt ID: (Human) P06729, (Human) P09564
Entrez Gene ID: (Human) 914, (Human) 924
adaptive immune response
immune system process
positive regulation of T cell cytokine production
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
interleukin-2-mediated signaling pathway
T cell activation
membrane raft polarization
apoptotic process
cell adhesion
cell surface receptor signaling pathway
natural killer cell activation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
heterotypic cell-cell adhesion
natural killer cell mediated cytotoxicity
regulation of T cell differentiation
cell-cell adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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