Immunogen sequence: EEVLWHTSVP FAENMSLECV YPSMGILTQV EWFKIGTQQD SIAIFSPTHG MVIRKPYAER VYFLNSTMAS NNMTLFFRNA SEDDVGYYSC SLYTYPQGTW QKVIQVVQSD SFEAAVPSNS HIVSEPGKNV TLTCQPQMTW PVQAVRWEKI QPRQIDLLTY CNLVHGRNFT SKFPRQIVSN CSHGRWSVIV IPDVTVSDSG LYRCYLQASA GENETFVMRL TVAEGKTDNQ YTLFVA; Positive Samples: Mouse lung; Cellular Location: Membrane, Single-pass type I membrane protein
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
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Protein Aliases: CD226; CD226 antigen; DNAM 1; platelet and T cell activation antigen 1; Platelet and T-cell activation antigen 1
Gene Aliases: BC051526; Cd226; DNAM-1; DNAM1; Pta1; TLiSA1
UniProt ID: (Mouse) Q8K4F0
Entrez Gene ID: (Mouse) 225825